Seed stage · Life science · San Diego
Unlocking the potential of exceptional life science technologies and entrepreneurs.
We fuel early-stage startups building R&D tools, platform technologies, and AI x Bio — solving today's roadblocks so tomorrow's discoveries and therapeutics can thrive.
17
Companies backed
3
Exits to Dexcom, Thermo Fisher & Nova Biomedical
45+
Years of operating experience
San Diego
Where we're based
Our thesis
We help grow the companies developing the tools to build that future.
Phase Two Ventures is a seed venture fund based in San Diego investing in early-stage life science tools, platform technologies, and AI x Bio to support the next generation of basic research, diagnostics, and therapeutics.
We aim to discover and support diverse science entrepreneurs with backgrounds in multi-omics, bioengineering, synthetic biology, and cell & gene therapies. The firm was co-founded by entrepreneurs with years of operational experience who understand the nuances of taking early technology toward commercial success. We put that experience to work with pre-seed startups by providing capital, coaching, and support.
Portfolio
Active investments
A cross-section of the companies we back, from lab automation to spatial biology and autonomous agents for science.

Augment Biologics
Next-gen glycoengineering for better biologics.

GelTech Labs
Lab automation for hydrogel scientists.
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Acurion
Transforming routine pathology slides into powerful diagnostic insights.
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Navega Therapeutics
AI-enabled zinc finger platform for gene therapies based on targeted epigenetic regulation.
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Morphos Bioscience
Spatial biology platform that maps tissues using standard sequencing.
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Potato
Autonomous agents for science and literature-based tools to plan and run new methods.
Visit site →Plus 5 more active companies and 6 prior investments, including three acquisitions.
Building the tools for tech + bio?
We back pre-seed and seed founders in life science tools, platform technologies, and AI x Bio.
